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SCIENTIFIC STUDIES ON INGREDIENTS

1. Vacha (Acorus calamus)

 

Calamus is a plant. The root (Rhizome) is used to make medicine. Despite Safety concerns, Calamus is used for gastrointestinal problems including ulcers, inflammation of the stomach lining (gastritis) intestinal gas (Flatulence), upset stomach, and loss of  appetite (anorexia) Calamus is also used as Calming medicine (Sedative), to induce sweating, and to treat Rheumatoid arthritis and Stroke.

Some people chew calamus to remove the smell of tobacco as a stimulant to increase their sense of well-being and as a hallucinogen. 

Antiulcer and cytoprotective properties

The ethanol extract of Ac was Studied in rats for its ability to inhibit gastric secretion and to Protect gastroduodenal mucosa against the injuries caused by pyloric ligation, indomethacin, reserpine and cysteamine administration and cyto destructive agents including 80% ethanol, 0.6m HCL, 0.2M NaOH and 25%Nacl An oral dose of 500mg/kg of the extract showed significant antisecretory i antiulcerogenic  activity in rats subjected to pyloric ligation, indo-methoacin, reserpine and cystamine administration. The extract had a highly – significant protective effect against cyto-destructive  agents. These findings support the use of the calamus for treating gastropathy in traditional medicine.

Antidiarrheal Activity

A study was undertaken to evaluate the effect of aqueous and methanol extracts of Ac rhizome for its antidiarrheal potential against castor oil-induced diarrhea in mice. The methanol plant extract was more effective than the aqueous plant extract against castor oil-induced diarrhoea. The methanol extract significantly reduced the induction time of diarrhea and the total weight of the fece.

 

2. Ajwain (Trachyspermum ammi)

 

Ajwain’s fruit possesses stimulant “Antispasmodic and carminative properties and is used traditionally as an Important Remedial agent for flatulence, atonic dyspepsia, diarrhea, abdominal tumors abdominal pains, piles and bronchial problems.

Laxative and purgative action:

Relieve constipation and promote bowel movements, thus eliminating Mala or waste products and promoting Health

Stimulant and digestive:

Promote energy, activity, and digestive process Hot in energy pungent in taste

Ajwain functions as a stomachic (promoting Appetite or aiding indigestion ) and laxative and is used as an appetizer. It might be helpful for conditions like piles, abdominal tumors, abdominal pain, vomiting, mouth diseases, etc

Potential use of Ajwain for digestion

Ajwain might help reduce irregular pains Of the intestines and stomach in both adults and children Taking ajwain with common salt and warm water may relieve any colicky (Sharp pain in the intestine)Pain due to gas accumulation, indigestion and infection in the intestine. Ajwain might be taken with buttermilk to relieve digestion-related problems

Potential use of Ajwain for diarrhea

Consuming ajwain Seeds might be a natural way to help deal with diarrhea or dysentery. A handful of ajwain seeds may be boiled and taken in a glass of water. This mixture can be cooled and consumed for diarrhea

 

3. Rock salt (Sendha namak)

 

Rock Salt is an excellent home remedy for digestive problems such as constipation, heartburn, bloating, stomach pain & vomiting.

 Rock salt is full of minerals and vitamins which improves digestion, promotes bowel movement, and helps to clean toxic products from the intestine. It also helps to improve the loss of appetite. The study result suggests that rock salt can stimulate insulin in the body which prevents sugar cravings. Rock salt can also be of help in losing weight.

Stimulates digestion:

 Firstly rock salt acts as an appetizer, especially when consumed as a pinch in conjunction with a piece of fresh ginger before meals. Second, it aids digestion by helping to stimulate the salivary gland in the mouth to release amylase, an enzyme.

Third, it helps to release HCl in the stomach, which breaks down our food into its absorbable or assimilable form.

Salt is also one of the leading sources of chloride. Healthy chloride levels are essential for manufacturing Hcl Substituting your regular salt with organic India pink Rock salt can help to make your meals more nutritious, delicious, and digestible.

 

4. Karchur (Curcuma zedoaria)

 

Curcuma zedoaria typically grows in India, Indonesia, and Taiwan. The species also is called “White turmeric” because of the white color at the interior of its rhizome. The rhizome oil has been reported to contain antioxidants such as curzerene and epicurzerene. The tuber extracts of curcuma zedoaria act as a carminative, digestive stimulant and exhibit antimicrobial action against Aspergillus niger, Bacillus subtilis, candida albicans, and  klebsiella pneumonia (Wilson et al. 2005). It also contains curcemenol and sesquiterpene, which possess anti-inflammatory, Antitumor, hepatoprotective, and neuroprotective effects.

Curcuzedoalide, found in the rhizomes of c. Zedoaria displays antiproliferative action against human gastric cancer cell lines by inciting apoptosis. (Jung et al. 2018)

Curcumin compound permits improved markedly intestinal absorption of curcumin and guarantees a greater tissue delivery than the traditional curcuminoid mixtures. So, curcumin phytosome has the potential to be exploited in many gastrointestinal diseases, both functional and organic.

 

5. Chitraka (Plumbago zeylanica)

 

Chitraka helps to improve the digestive system due to its Deepana (appetizer) and Pachana (digestion) properties It also helps manage atherosclerosis as it prevents the deposition of fatty substances in arteries and maintains the blood flow in the body.

Indigestion:

Indigestion is termed as Agnimandya that occurs due to an imbalance of pitta dosha. Whenever the consumed food is left undigested due to mandagni (low digestive fire), it results in the formation of Ama (toxic remains in the body due to improper digestion) which causes indigestion. In simple words, we can say that indigestion occurs due to an incomplete process of digestion. Chithraka helps to manage indigestion by digesting the Ama due to its Deepana and pachana properties It even helps to balance the pitta dosha. Chitraka helps to manage ulcers due to its Strong   antioxidant activity Antioxidants help prevent wound formation caused by several ulcer – Causing agents various scientific Studies also suggest that it reduces Injuries on the stomach wall and prevents the formation of ulcers

Ayurvedic view

Ulcers usually occur due to weak or poor digestion chitraka helps manage ulcers due to its Deepana and Pachana properties. This helps improve digestion and prevent the formation of ulcers

Chitraka root is beneficial to treat digestive tract disorders like indigestion. Chithrak roots can be used after drying and grinding to powdered form. Have this powder once or twice a day with lukewarm water to get rid of Indigestion.

 

6. Pippalimoola (Piper longum)

Pippali is used to improve appetite and digestion as well  as treat stomach ache, heartburn, indigestion, intestinal gas, diarrhea, and Cholera. Pippali contains a chemical called piperine. Piperine may be able to fight certain parasites that can infect people. It also seems to change the lining of the intestines. This change allows some drugs and other substances taken by mouth to be better absorbed by the body. Consuming pippali powder might be useful in managing constipation by promoting bowel movements due to its laxative properties.

Diarrhea is known as Atisar in Ayurveda. It is due to improper food, Impure water, toxins, mental stress, and Agnimandya. All these factors are responsible for aggravating vata. This aggravated vata brings fluid in the intestine from various tissues of the body and mixes with stool

This leads to loose, watery motion or diarrhea. Pippali powder helps to control diarrhea because it has Vata-balancing properties. It also Improves the digestive fire because of Its Deepana property which helps to control unusual motion frequency 

Benefit of Pippali for flatulence

Pippali helps to manage Stomach Ache. due to gas or flatulence. flatulence is caused due to an imbalance of vata & Pitta dosha. Low pitta dosha and aggravated vata dosha result in low digestive fire, thus Impairing digestion Impaired digestion leads to gas formation and causes  Stomach Ache. Taking pippali powder helps to correct digestive fire. because of its Anuushna potency. This prevents gas formation and thus Stomach aches Pippali for indigestion.

Pippali helps to manage indigestion. According to Ayurveda, indigestion  means the state of incomplete process of digestion. The main reason for indigestion is aggravated kapha which causes Agnimandya. Taking pippali powder helps to improve Agni and digest the food easily. This is due to Its Deepana and pachana properties respectively

 

7. Shunti (Zingiber officinalis.)

Ginger is also used as a home remedy and is of immense value in treating various gastric ailments like constipation, dyspepsia, belching, gastritis, epigastric, bloating, gastric, discomfort, gastric ulcerations, indigestion, nausea and vomiting, Scientific studies have validated the ethnomedicinal uses  of Ginger is also shown to be effective in preventing gastric ulcers induced by nonsteroidal antiinflammatory drugs( NSAIDS like indomethacin, aspirin ) reserpine, ethanol, stress(hypothermic and Swimming), acetic acid and  Helicobacter Pylori Induced gastric ulcerations in laboratory animals various preclinical and Clinical studies have also shown ginger to possess antiemetic effects against different emetogenic Stimuli. However, conflicting reports especially in the Prevention of chemotherapy-induced nausea vomiting, and motion sickness prevent us from drawing any firm conclusion on its effectiveness as a Spectrum antiemetic action ginger and Anti-inflammatory, antioxidant, and anti-ulcer effects of ginger have been proven in many Scientific studies, and some of the ancient applications of ginger as a home remedy has been confirmed in human. In this  review, we summarised the current evidence on the effect of ginger consumption on gastrointestinal disorders based on clinical trials. Data indicate that a divided lower daily dosage of 1500mg ginger is beneficial for nausea relief

Gastric Emptying and Dyspepsia

Ginger is an Important dietary agent that possesses a Carminative effect, decreases pressure on the lower esophageal sphincter, reduces intestinal cramping,  and preventi dyspepsia, flatulence and bloating, (Ali et al 2008; Chrubasilc pittler and Roufogalis (2005),loh siriwat, Rukkiat)A clinical trial investigated the effect of ginger extract on gastrointestinal motility and showed a Significant increase in gastrointestinal motility in the Intervention group in comparison with the placebo (Mickleflad et al, 1999). Wu et al (2008) showed that ginger accelerates  gastric emptying and stimulates antral contractions in healthy individuals. Studies on patients with functional dyspepsia have shown the same results with no alterations In the fundus dimension, gastrointestinal Symptoms, or Serum level of gut peptides such as GLP-1, motilin, and ghrelin (Hyetal 2011)

Nausea and vomiting

The studies have shown that ginger in a dose of 1g/day is effective in pregnancy nausea and Vomiting with no significant side effects. American College of Obstetricians and Gynecologists (ACOG) and the National Institute for Health and Clinical Excellence have accepted ginger as a remedy for nausea and vomiting during early pregnancy.

 

8. Hingu (Ferula Asafoetida)

Hingu  is highly beneficial in curing digestive disorders and flatulence. It is loaded with fibre aids in digestion and maintains the regular bowel movements in the body. Hingu being rich in fibre aids in digestion it provides relief from stomach problems like gastritis, bloating abdominal pain flatulence and promotes Overall digestive health due to its antimicrobial properties, it prevents the growth of flora in the intestines and reduces the chance of Stomach infection.

The odor of asafoetida is imparted to the breath, flatus, Secretion, and gastric eructations.

Its properties are antispasmodic, expectorant Stimulant, emmenagogue and vermifuge.

Effect of Ferula asafoetida on the gastrointestinal tract:

The herb is an effective remedy for several diseases of the stomach. It is one of the best remedies available for flatulence and is an essential ingredient for most of digestive powders. In case of flatulence and distension of the Stomach asafoetida Should be dissolved in hot water and a Pad of cloth steeped in it may be used for fomenting the abdomen

Colloidal solution, administered orally to rats at a dose of 50 mg kg, 60 minutes before the experiment, produced significant Protection against gastric ulcers induced by 2 hrs cold restraint Stress, aspirin, and 4 hrs pylorus ligation.

Gum extract, administered to isolated guinea pig ileum at a dose of 3mg/ml, produced a decrease of Spontaneous contraction to 54+ or -7% of control.

Exposure of pre-contracted ileum by acetylcholine,  histamine, and kcl to ferula gum extract produced a concentration-dependent relaxation

Asafoetida, administered orally to rats at a dose of 2500 mg% for 8 weeks decreased level of phosphatases and Sucrase in the small intestine